Stability Analyzer TURBISCAN LAB

The world reference stability analyzer TURBISCAN LAB enables fast and sensitive identification of destabilization mechanisms (creaming, sedimentation, flocculation, coalescence, and more). A temperature-controlled measurement cell allows either stability monitoring at specific storage temperatures or acceleration of the destabilization process with a temperature increase up to 60°C.

The TURBISCAN LAB can be used in both R&D and QC labs for the development and routine control of raw materials and final product formulations. The TURBISCAN technology not only detects stability evolution at an early stage (up to 1,000 times faster compared to visual testing), but also quantifies global formula alteration with the Turbiscan Stability Index (TSI) scale.

Stability Analyzer TURBISCAN LAB The World Leader in Stability Analysis

  • Static Multiple Light Scattering (SMLS) technology
  • 1 measurement position
  • Temperature range from room temperature (RT) up to 60°C, to observe destabilizations in real usage and storage conditions
  • Accelerated destabilization detection – up to 1,000 x faster than visual observation
  • Real stability: sample stability analysis without the need for dilution or mechanical stress, in concentrations up to 95%
  • Quantitative measurements of dispersion stability and shelf-life, migration velocity, particle size diameter, and other parameters
  • One-click stability ranking with the Turbiscan Stability Index
  • Barcode reader for easy sample management
  • Convenient: Plug & Play, free license software on multiple computers, limited footprint ...

Stability Analyzer URBISCAN LAB Typical Applications

Whenever you are working with suspensions, emulsions, colloids, or foam, the TURBISCAN is your ideal characterization companion. The TURBISCAN series is used in various industries such as pharmaceuticals, cosmetics, food and beverage, paints and coatings, oil and gas, batteries, agrochemicals, chemistry, and much more.

 

emulsions

  • Cosmetic creams and lotions
  • Dairy products and beverages, flavor emulsions
  • Pharmaceutical parenteral and topical forms
  • Metalworking fluids
  • Agrochemical: fertilizers, pesticides, ...
  • Petroleum emulsion

suspensions

  • Paints, inks, and coatings
  • Drug & vaccine suspension
  • Make-up and sunscreen
  • Chemical & polymer industry
  • Ceramics and catalysts
  • Battery slurries
  • Electronic slurries

colloids & nanoparticles

  • Drug delivery system: LNP, Liposomes, ...
  • Research on nanoparticles and nanoparticle suspension
  • Polymer and biopolymer dispersion
  •  

 

... and many more!

Application examples

Fast Detection of Settling Particles Sedimentation

The TURBISCAN technology offers a significantly faster (up to 1,000 times) and more reliable detection of sedimentation compared to visual observation. Furthermore, naked-eye observation makes it difficult to calculate the migration rate and is prone to error and misinterpretation. In contrast, the TURBISCAN technology provides a fast and non-destructive way to detect and quantify sedimentation and particle size over time and can detect even small changes in highly concentrated samples without any dilution or mechanical stress. This makes it ideal for analyzing complex suspensions and formulations, and getting a quicker, reliable, and more accurate answer on sedimentation monitoring. 

Fast Detection of Droplet Migration Creaming of Emulsions

When it comes to measuring droplet migration and creaming behavior in emulsion systems, the TURBISCAN technology has several advantages for formulators. On one hand, it provides a fast measurement (up to 1,000 times faster than visual observation) of native samples and a non-destructive way to detect and measure droplet migration. On the other hand, the migration rate can easily be determined and helps the formulator to compare formulas, making it ideal for analyzing complex emulsions with a wide range of droplet sizes and concentrations. Additionally, the TURBISCAN technology provides insights into the mechanisms driving droplet migration, which can be used to improve formulation and processing conditions. Overall, the use of TURBISCAN technology in emulsion analysis leads to faster, more accurate, and more reliable results compared to traditional methods.

 

Save Time to Measure Physical Stability Formulation: Stability Measurement and Shelf-Life Estimation

The TURBISCAN has been extensively used to measure the physical stability of formulations and colloidal systems. This technology helps the formulator to save time and precisely rank and quantify the samples’ stability in different trials or batches. It applies to native samples, even on very highly concentrated formulations. Not only saving time, the TURBISCAN also provides destabilization speed and metrics as well as robust analytics to make shelf-life predictions. The TURBISCAN technology follows ISO/TR 13097:2013’s recommendations and is ideal when it comes to quickly and accurately measuring stability. Stop the guesswork and make decisions based on facts!

 

What Can Be Measured Can Also Be Improved Stability Mapping: Emulsions and Suspensions

Measuring the stability of emulsions and formulations is traditionally done by visual observations. In addition to being long and tedious, the visual inspection of emulsion destabilization usually ends up with a pass / fail answer. This is suboptimal for fine-tuning the ideal concentration of surfactants or stabilizers to be added to reach the desired shelf-life. The TURBISCAN is a great help in this regard; not only does it save a huge amount of time to detect the destabilization, but it also provides a value based on the instability and ranks different formulas as a function of their shelf-life. It hence produces objective and repeatable data to make a better, greener, and safer product.

Example image of Superabsorbent Polymers (SAP)

Stable Products for Safer and More Efficient Pharmaceutical Suspensions Vaccine and Parenteral Dispersions

Stability and shelf-life testing are essential for pharmaceutical products and drugs. Destabilization or instabilities in vaccines, parenteral dispersions, or pharmaceutical products can have a major impact on product efficacy, and in some cases, on patient safety. While many techniques are available, the TURBISCAN offers in-situ, non-dilution, and non-destructive measurements to detect destabilization and save time therein. It provides a clear, precise, and objective stability measurement, essential to making fast and right decisions in R&D or quality control. The TURBISCAN has been intensively used to study the stability and redispersion capability of vaccines, as well as of parenteral and injectable dispersions and providing scientists with a deep insight into the dispersion state and its evolution.

 

Homogenous Slurries for Higher Battery Performance Improving Battery Efficiency

There is an exponential demand for energy storage and batteries, either to cover our need for mobility and communication or to match environmental challenges. Lithium-ion batteries are the most widely used technology, and one of the key steps in developing and manufacturing them is the slurry formulation (used on the electrodes), ensuring the final battery quality. This slurry is usually highly concentrated and dark (due to a high concentration of carbon black) and using conventional light scattering techniques for evaluation is challenging or requires an important amount of dilution. The TURBISCAN has been successfully used to monitor the stability of these slurries and helps the formulator to optimize the formulation, test the production, and identify new raw materials.

To find the best solution for your particle characterization needs, visit our application database

Measurement Results in Just a Few Clicks TURBISOFT Software for the TURBISCAN LAB

Data acquisition, interpretation, and export are done with TURBISOFT, the dedicated and intuitive software for the TURBISCAN range. TURBISOFT has been developed for and is continuously optimized towards more intuitive and straightforward data analysis, hence saving time and helping users to get the results they need in a few clicks.

  • Intuitive and straightforward navigation
  • Fast and robust stability comparison thanks to the TSI algorithm
  • Advanced calculation for deep data analysis: migration rate, mean particle size evolution, phase separation, and more
  • Ideal for very fast kinetic or variation measurements: Data acquisition with up to 10 measurements per second
  • Stay up to date: free license – free software updates
  • Need to use multiple computers? This multi-user software has you covered
  • Data export as easy as copy-paste
  • Video recording of sample destabilization for up to 6 samples
  • Fully guided calibration check-up procedure
  • Multi-language support: English, Spanish, French, Chinese, Japanese, German, and more

Dispersibility & stability analyzer TURBISCAN DNS Accessories and Options

The TURBISCAN DNS comes with all you need to perform dispersibility and stability studies:

Standard Vials (20 ml)

Cylindric glass vials have a recommended volume of approximately 20 ml. They are disposable to avoid chemical or bacterial contamination and decrease labor costs for washing and drying. The vials are closed thanks to a cap and a disposable PTFE seal to prevent evaporation in case of elevated temperature. These vials are meant to reproduce your visual stability test.

Small Volume (4 ml)

Small sample volume? No problem. Small-volume vials and the specific adapter are available. The measurement can be done with as few as 2 ml. Another good news: the sample can be fully recovered, and TURBISCAN measurement is non-contact / non-destructive.

On-Demand Adaptors (for Syringes, Pressurized Vials)

You have special needs, and we understand this! Our development team loves challenges: on-demand adapters can be offered (pre-filled syringes, pressurized vials, ...). Perfect to study the stability in specific conditions (pressure) or for Quality Control.

Open-Bottom cells - For Viscous and Fragile Samples

There are samples that are either difficult to transfer or too fragile to be poured – the coring vials set helps to bypass this problem. The open base (which is manually closed with a stopper) allows a sticky sample or foam to be easily removed with the coring vials.

Calibration Standards

Each TURBISCAN comes with a set of standards to check instrument calibration. The TURBISCAN software, TURBISOFT, guides you step by step and once the procedure is finished, the software gives an "OK" signal. The test and results are saved, and the instrument checking procedure can be tracked.

Particle Size Distribution

The TURBISIZE software can measure the distribution of particle size (ISO13317) and the distribution of migration speed for any data obtained with a TURBISCAN, without any need to dilute, prepare, or modify the sample.

Stability Analyzer TURBISCAN LAB Technical Data

Acquisition scan step 20 µm
Automatic sample recognition (bar-code) Yes
CE Certified Yes
Dimensions 26 x 28 x 25 cm
Standards ISO/TR 13097:2013, ISO/TR 18811:2018, ISO 13317-3:2001, ISO/TS 22107:2021, ISO/TS 21357:2022
Measured size range 10 nm - 1 mm
Wavelength 880 nm
Measuring Principle Static Multiple Light Scattering (SMLS)
Particle size distribution Yes (additional software required)
Number of Samples 1
Reproducibility / Repeatability on latex standards 0.05%
Sample concentration 0.0001 - 95%
Sample volume 2 - 20 mL
Software TurbiSoft Lab
Temperature range RT - 60°C
Weight 8 kg

Stability Analyzer TURBISCAN LAB Downloads

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