High-throughput stability analyzer TURBISCAN AGS

The TURBISCAN technology offers a significantly faster (up to 1,000 times) and more reliable detection of sedimentation compared to visual observation. Furthermore, naked-eye observation makes it difficult to calculate the migration rate and is prone to error and misinterpretation. In contrast, the TURBISCAN technology provides a fast and non-destructive way to detect and quantify sedimentation and particle size over time and can detect even small changes in highly concentrated samples without any dilution or mechanical stress. This makes it ideal for analyzing complex suspensions and formulations, and getting a quicker, reliable, and more accurate answer on sedimentation monitoring. 

When it comes to measuring droplet migration and creaming behavior in emulsion systems, the TURBISCAN technology has several advantages for formulators. On one hand, it provides a fast measurement (up to 1,000 times faster than visual observation) of native samples and a non-destructive way to detect and measure droplet migration. On the other hand, the migration rate can easily be determined and helps the formulator to compare formulas, making it ideal for analyzing complex emulsions with a wide range of droplet sizes and concentrations. Additionally, the TURBISCAN technology provides insights into the mechanisms driving droplet migration, which can be used to improve formulation and processing conditions. Overall, the use of TURBISCAN technology in emulsion analysis leads to faster, more accurate, and more reliable results compared to traditional methods.

The TURBISCAN has been extensively used to measure the physical stability of formulations and colloidal systems. This technology helps the formulator to save time and precisely rank and quantify the samples’ stability in different trials or batches. It applies to native samples, even on very highly concentrated formulations. Not only saving time, the TURBISCAN also provides destabilization speed and metrics as well as robust analytics to make shelf-life predictions. The TURBISCAN technology follows ISO/TR 13097:2013’s recommendations and is ideal when it comes to quickly and accurately measuring stability. Stop the guesswork and make decisions based on facts!

Measuring the stability of emulsions and formulations is traditionally done by visual observations. In addition to being long and tedious, the visual inspection of emulsion destabilization usually ends up with a pass / fail answer. This is suboptimal for fine-tuning the ideal concentration of surfactants or stabilizers to be added to reach the desired shelf-life. The TURBISCAN is a great help in this regard; not only does it save a huge amount of time to detect the destabilization, but it also provides a value based on the instability and ranks different formulas as a function of their shelf-life. It hence produces objective and repeatable data to make a better, greener, and safer product.

Stability and shelf-life testing are essential for pharmaceutical products and drugs. Destabilization or instabilities in vaccines, parenteral dispersions, or pharmaceutical products can have a major impact on product efficacy, and in some cases, on patient safety. While many techniques are available, the TURBISCAN offers in-situ, non-dilution, and non-destructive measurements to detect destabilization and save time therein. It provides a clear, precise, and objective stability measurement, essential to making fast and right decisions in R&D or quality control. The TURBISCAN has been intensively used to study the stability and redispersion capability of vaccines, as well as of parenteral and injectable dispersions and providing scientists with a deep insight into the dispersion state and its evolution.

There is an exponential demand for energy storage and batteries, either to cover our need for mobility and communication or to match environmental challenges. Lithium-ion batteries are the most widely used technology, and one of the key steps in developing and manufacturing them is the slurry formulation (used on the electrodes), ensuring the final battery quality. This slurry is usually highly concentrated and dark (due to a high concentration of carbon black) and using conventional light scattering techniques for evaluation is challenging or requires an important amount of dilution. The TURBISCAN has been successfully used to monitor the stability of these slurries and helps the formulator to optimize the formulation, test the production, and identify new raw materials.